What is Human Coronavirus 229e ?

Human Coronavirus 229e Code name (HCoV-229e) is a type of coronavirus. There are numerous deadly variations of viruses which affects breathing and not only put animals at risk, but humans as well. Ineffective people-to-people transmission of viruses that are able to successfully pass from animals to humans may at first limit the spread. However, individuals may come into contact with the contagion by holding on to unclean surfaces. The human coronavirus 229e is an enveloped virus, this mean that the virus has an outer casing. Two other examples of enveloped viruses that you may have heard of are SARS (severe acute respiratory syndrome) and MERS (Middle East respiratory syndrome).

Reports indicate that the human coronavirus 229e is catching to an individuals lung cells for about 120 hours on surfaces that are not chemically engineered to kill, defuse, or orchestrate an effect once dangerous organisms come into contact with them (biocide). These nonbiocidal surfaces are found everywhere, unless you are inside a laboratory you are more likely to see it all around you. Some well known examples of nonbiocidal materials are, Teflon, polyvinyl chloride (pipes, toys, containers etc), ceramic tile, glass, silicone rubber and the list goes on.

Copper alloy surfaces are known to kill viruses that cause stomach flu and diarrhea. New studies also show that surfaces that are made of copper alloys rendered the human coronavirus 229e inactive. When exposed to copper alloys the virus hereditary details encoded in its RNA were destroyed.  It also permanently changed the structure of the virus, for example breaking down the envelope. Therefore, one way in which to reduce the spread of viruses on frequently touched surfaces like elevator buttons, door handles, rails, furniture, etc. is to employ the integration of copper alloys.

Another way to reduce the spreading of the virus is for business and individuals alike to adapt and implement strict cleaning regimen for frequently touched areas, with the use of appropriate chemicals. Some examples are using Accelerated hydrogen peroxide and alcohol based cleaning products to wipe high touch surfaces.

What are the Signs and symptoms of human coronavirus 229e?

It is important to know that you may be infected with human coronavirus 229e and not know. This is mainly because of two reasons, the first is that you may contract the virus and you are not feeling ill. Secondly the symptoms that you are seeing may be mistaken for that of the common cold or flu. Social Distancing becomes more critical when considering these two variables, because, if an infected person transmits Covid 19 to a person that has prior medical challenges like asthma, bronchitis, etc. it could lead to that person losing their life. Symptoms are reported to take up to fourteen days (14) to show up after being exposed to human coronavirus 229e (Covid 19).

Symptoms of human coronavirus 229e includes but not limited to:
Cough
Fever
Difficulty breathing
Pneumonia in both lungs

Who are most vulnerable to human coronavirus 229e?

Records would indicate that the elderly are the most susceptible to the virus, individuals 60 years and over, also persons with pre-existing medical issues.

Are children and infants at higher risk?

Children with an impaired immune system may have a critical predisposition from human coronaviruses and its variations, including human coronavirus oc43, human coronaviruses nl63, human coronaviruses hku1 and human coronaviruses 229e.

Human respiratory track disease whether in the upper or lower respiratory track are a result of coronaviruses. Estimates are that every year one (1%) to ten (10%) percent of people experience symptoms resembling a cold, potentially because they were infected with human coronavirus nl63 (HCoV-NL63). Coronaviruses come in four genera of which human coronavirus NL63 falls in the first genera (alphacoronavirus), the other three are betacoronavirus, gammacoronavirus, and deltacoronavirus. The N protein shell of the virus aids in RNA packing, as well it connects the envelope to the N protein shell of the virus. It also plays a role in a number of other processes, such as eluding the body’s immune system and replicating itself.

Human coronaviruses are known to account for a (3rd) third of common colds in adults. However, the role they play in causing illness to children have not been clear. This is largely due to challenges surrounding how viruses are studied, and diagnosis. New techniques are being created to monitor these infections and to determine their medical significance. Lately there has been new found interest in human coronaviruses because of the recognition of severe acute respiratory syndrome (SARS) in the year 2002 and 2003. Human coronaviruses nl63 and hku1 has since been identified in children. Also, HCoV-229E has been seen as a possible force in contracting viral respiratory infections for higher risk infants and new borns in hospitals.

Coronavirus vs rhinovirus

It is well known by now that the common cold is most often a result of contracting human Coronaviruses and human rhinoviruses in individuals that have a relatively normal immune response to producing antibody. The upper respiratory tract in epithelial cells is the primary location for viruses to multiply. Studies showed that in young children and infants these viruses caused bronchiolitis and pneumonia. Then in older adults it causes pneumonia.

Early wheezing has been identified as an indicator of rhinovirus and subsequently a risk factor for asthma. Poor lung functional and tendency to exaggerate the production of an immune response to predominantly innocuous environmental substances and also attributed to rhinoviruses.
Two of the reasons for this happen includes damage to the bronchial epithelium and genetic proclivity.

Rhinoviruses RNA differ genetically, and comes from the Enterovirus genus which is apart of the Picornaviridae family. There are 160 known differentiations of rhinovirus genotypes. These are placed into classifications, they are A, B, and C. For acute asthma, lower airways sickness, and more critical sicknesses Rhinovirus-A and Rhinovirus-C appear to be more prominent than Rhinovirus-B.

Really bad wheezing early in children due to rhinovirus could be a risk indicator for later development of asthma.

Does lysol kill coronavirus

Lysol Disinfectant Sprays containing ethyl alcohol with a concentration of 60% or higher is effective to disinfect surfaces that may be exposed to human coronavirus 229e (Covid 19). However, it is very important to note how long to have to solution on the contaminated surface (Contact Time) for it to have the desired effect against Covid 19. For Lysol to be effective its recommended contact time is 10 minutes. The table below shows a list of active ingredients and contact times for other suitable disinfectants for human coronavirus 229e.

Key Takeaway

Distancing yourself from other people, wearing a mask and effectively washing your hands is potentially the most adequate way of protecting yourself, your family, and the public at large.

Reference

Note: Please copy and paste links in your browser.

Human Coronavirus 229E Remains Infectious on Common Touch Surface Materials
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659470/

Coronavirus disease covid-19
https://www.canada.ca/en/public-health/services/diseases/coronavirus-disease-covid-19.html

Characteristics and Outcomes of Coronavirus Infection in Children: The Role of Viral Factors and an Immunocompromised State
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437838/

Structural Characterization of Human Coronavirus NL63 N Protein
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432860/

Outbreaks of human coronavirus in a paediatric and neonatal intensive care unit
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087120/#CR25

Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipients
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837322/

Rhinovirus species and clinical characteristics in the first wheezing episode in children
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140033/

Interim List of Household Products and Active Ingredients for Disinfection of the COVID-19 Virus
https://www.nea.gov.sg/our-services/public-cleanliness/environmental-cleaning-guidelines/guidelines/interim-list-of-household-products-and-active-ingredients-for-disinfection-of-covid-19

Efficacy of various disinfectants against SARS coronavirus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132504/